Zach Cregger’s ‘Resident Evil’ blows away franchise opening weekend record

The ‘Weapons’ director’s reboot debuted with $60M, easily beating the previous high mark of $26.7M.

Austin Abrams in Resident Evil
Austin Abrams in Resident Evil. / Sony

Hello! Welcome to The Box Office Report for the weekend of Sept. 18-20, 2026.

1. Resident Evil

Weekend gross: $60M
Total domestic gross: $60M
Last weekend: New release
Percent drop: NA

The newest Resident Evil movie had a historic opening weekend for the franchise. Not only is its $60 million debut easily the biggest for a Resident Evil movie — Resident Evil: Afterlife’s $26.7 million was the previous high mark — but the reboot made more in North America this weekend than any previous Resident Evil movie did over its entire domestic run. By the time we get actual weekend numbers on Monday, there’s a solid chance Weapons director Zach Cregger’s entry into the series will have actually topped Afterlife’s $60.1 million haul.

What a huge bounce-back for the Resident Evil franchise. The original run of movies began with 2002’s Resident Evil, with Milla Jovovich leading five sequels after that, culminating in 2016’s Resident Evil: The Final Chapter. The 2021 reboot attempt immediately stalled out as Resident Evil: Welcome to Raccoon City opened with just $5.3 million.

Does this also prime the box office for Whalefall, Austin Abrams’s next film?

2. Practical Magic 2

Weekend gross: $12.2M
Total domestic gross: $50M
Last weekend: 1st
Percent drop: 59

A 59 percent drop between its opening weekend and this weekend isn’t great for Practical Magic 2, but the legacy sequel’s current $50 million domestic haul has already topped its predecessor’s $46.9 million North America total. (We don’t talk about inflation at Popculturology.)

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3. Spider-Man: Brand New Day

Weekend gross: $6.5M
Total domestic gross: $944.5M
Last weekend: 2nd
Percent drop: 23

It’s weird seeing Spider-Man: Brand New Day in third place, but time comes for all theatrical releases. With a $944.5 million haul, the latest Spider-Man film has passed Star Wars: The Force Awakens ($936.7 million) for the No. 1 spot on the all-time domestic chart.

Brand New Day also sits at No. 3 on the all-time worldwide chart, with its $2.456 billion total currently settling between Avatar: The Way of Water’s $2.334 billion and Avengers: Endgame’s $2.799 billion.

4. The Odyssey

Weekend gross: $4.9M
Total domestic gross: $609.8M
Last weekend: 3rd
Percent drop: 35

Based on their previous trajectories, I thought we’d see The Odyssey skip past Spider-Man: Brand New Day this weekend, but thanks to the latter’s spectacular 23 percent weekend-to-weekend hold, the Christopher Nolan film shifted down to the No. 4 slot.

5. Coyote vs. Acme

Weekend gross: $4.5M
Total domestic gross: $54.8M
Last weekend: 5th
Percent drop: 30

Coyote vs. Acme, still in the top five! What is dead will never die!

Box office numbers via The Numbers and Box Office Mojo based on Sunday estimates.

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Popculturology is a publication of The Omnicosm.
Issue No. 495

Popculturology is written and produced by Bill Kuchman.
Copyediting by Tim Kuchman.

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