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# Zach Cregger’s ‘Resident Evil’ blows away franchise opening weekend record
- URL: https://www.theomnicosm.com/popculturology-box-office-report-resident-evil/
- Published: 2026-09-21T11:00:24.000Z
- Updated: 2026-09-21T11:00:24.000Z
- Description: The ‘Weapons’ director’s reboot debuted with $60M, easily beating the previous high mark of $26.7M.
- Author: Bill Kuchman
- Tags: Popculturology • The Box Office Report, Popculturology, Resident Evil, Practical Magic, Spider-Man, Spider-Man: Brand New Day, MCU, Marvel, The Odyssey, Coyote vs. Acme

Hello! Welcome to **The** **Box Office Report** for the weekend of Sept. 18-20, 2026.

## 1\. Resident Evil

*Weekend gross: *$60M** 
*Total domestic gross: *$60M** 
*Last weekend: *New release** 
*Percent drop: *NA**

The newest *Resident Evil* movie had a historic opening weekend for the franchise. Not only is its $60 million debut easily the biggest for a *Resident Evil* movie — *Resident Evil: Afterlife*’s $26.7 million was the previous high mark — but the reboot made more in North America this weekend than any previous *Resident Evil* movie did over its entire domestic run. By the time we get actual weekend numbers on Monday, there’s a solid chance *Weapons* director **Zach Cregger**’s entry into the series will have actually topped Afterlife’s $60.1 million haul.

What a huge bounce-back for the *Resident Evil* franchise. The original run of movies began with 2002’s *Resident Evil*, with **Milla Jovovich** leading five sequels after that, culminating in 2016’s *Resident Evil: The Final Chapter*. The 2021 reboot attempt immediately stalled out as *Resident Evil: Welcome to Raccoon City* opened with just $5.3 million.

Does this also prime the box office for *Whalefall*, **Austin Abrams**’s next film?

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## 2\. Practical Magic 2

*Weekend gross: *$12.2M** 
*Total domestic gross: *$50M** 
*Last weekend: *1st** 
*Percent drop: *59**

A 59 percent drop between its opening weekend and this weekend isn’t great for *Practical Magic 2*, but the legacy sequel’s current $50 million domestic haul has already topped its predecessor’s $46.9 million North America total. (We don’t talk about inflation at **Popculturology**.)

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## 3\. Spider-Man: Brand New Day

*Weekend gross: *$6.5M** 
*Total domestic gross: *$944.5M** 
*Last weekend: *2nd** 
*Percent drop: *23**

It’s weird seeing *Spider-Man: Brand New Day* in third place, but time comes for all theatrical releases. With a $944.5 million haul, the latest Spider-Man film has passed *Star Wars: The Force Awakens* ($936.7 million) for the No. 1 spot on the all-time domestic chart.

*Brand New Day* also sits at No. 3 on the all-time worldwide chart, with its $2.456 billion total currently settling between *Avatar: The Way of Water*’s $2.334 billion and *Avengers: Endgame*’s $2.799 billion.

## 4\. The Odyssey

*Weekend gross: *$4.9M** 
*Total domestic gross: *$609.8M** 
*Last weekend: *3rd** 
*Percent drop: *35**

Based on their previous trajectories, I thought we’d see *The Odyssey* skip past *Spider-Man: Brand New Day* this weekend, but thanks to the latter’s spectacular 23 percent weekend-to-weekend hold, the **Christopher Nolan** film shifted down to the No. 4 slot.

## 5\. Coyote vs. Acme

*Weekend gross: *$4.5M** 
*Total domestic gross: *$54.8M** 
*Last weekend: *5th** 
*Percent drop: *30**

*Coyote vs. Acme*, still in the top five! What is dead will never die!

*Box office numbers via The Numbers and Box Office Mojo based on Sunday estimates.*

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